The Priory Pub in Micklegate joins the rest of the pubs in the Wear Inn Pub portfolio which have been put up for sale on the market.
It follows the appointment of new administrators in November of last year.
A busy marketing campaign and a strong level of demand is expected for the sale.
Emma Turnbull, associate director at Avison Young’s Newcastle office, said: “This sale offers a rare opportunity for a wide range of purchasers to acquire an established, strong performing pub group in a fairly tight geographic area and with a quality track record.
"The pubs have been well managed since our client’s appointment and have traded well over the festive period."